The direction and profile of the unit's activity in the aspect of own research

11 marca, 2021 10:30:00

dr hab. Tomasz Dziaman

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Farmaceutyczny Collegium Medicum w Bydgoszczy, Katedra Biochemii Klinicznej

Streszczenie pracy:

The Department of Clinical Biochemistry, practically from the beginning of its existence, has been dealing with research on the molecular pathogenesis of cancer and the use of molecular biology, genomics and proteomics methods for early detection, optimization of treatment and development of new methods of cancer therapy. For many years, the main area of research conducted in the Department was analyzes determining the level of oxidative DNA damage, the influence of various factors on their formation (diet, chemotherapy, hypoxia, oxidative stress, antioxidants, etc.) and the functioning of repair / removal systems for these modifications from the human body. Over the last decade, the Department of Clinical Biochemistry has significantly expanded its scope of scientific research, including methylation and demethylation products in the pool of analyzed DNA modifications. In this way, it has become part of the currently fashionable trend of epigenetic research, which brings with it a lot of hope for the development of better methods to fight cancer
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